Witnesses say they heard the 30-something male hiker screaming and yelling about 4 p.m. Monday from a gulley area about 150 yards off the trail.
The man tried to run after being attacked, but collapsed behind a rock. Witnesses say he was coated in bees as he waved a shirt above his head and screamed for help.
Several people tried to run to the hiker's aid, but they couldn't get close. One man came within ten feet and was repeatedly stung himself.
Two brothers say they then tried to help, but were warned to stay back at least 50 feet because the bees were so dangerous. Even police and park rangers could not help the hiker.
By the time a special technical rescue team with the Phoenix Fire Department arrived, the man had been under attack for 2 hours.
Six members of the rescue unit donned special bee suits with helmets, taped up their wrists to close up any holes and started down the mountain.
After a long hike into the preserves, and another hike off trail to reach the man, they were finally able to give him some relief.
They stabilized the man and gave him plenty of fluids. But the bees persisted.
The crews used a basket tied to a rescue helicopter to pull the man out of the preserves and to a waiting ambulance.
A Phoenix Fire Department spokesperson says the man suffered hundreds of bee stings.